Applications of Electroporation

Electroporation — the use of controlled electric pulses to permeabilise cell membranes — underpins a remarkably diverse range of technologies. Explore the fields below, each described by leading contributors from the ISEBTT community.

Oncology

Reversible electroporation exploits a simple biophysical principle with profound therapeutic consequences: short, high-intensity electric pulses transiently destabilise the plasma membrane, creating a window of increased permeability.

IRE in Oncology

Irreversible electroporation (IRE) has established a clinical niche as a nonthermal ablation technique for eradicating unresectable tumors, particularly those near critical vascular structures such as blood…

Vascular Malformations

Vascular malformations are congenital anomalies of the vasculature that persist and grow throughout life, encompassing slow-flow venous and lymphatic lesions as well as fast-flow arteriovenous malformations.

Cardiac Ablation (PFA)

Pulsed Field Ablation (PFA) is a disruptive technology in cardiac electrophysiology, transitioning rapidly from an experimental concept to widespread clinical implementation.

Veterinary Medicine

Electroporation, the use of controlled electric pulses to increase cell membrane permeability, is an established technology in veterinary oncology.

Food Processing

The food industry faces the challenge of producing safe, nutritious and high-quality foods while reducing energy and water consumption, improving the use of raw materials and…

Environment

The environment encompasses the natural and built surroundings in which living organisms exist and interact.

Engineering

Electroporation represents one of the most successful examples of how engineering can transform a fundamental biophysical phenomenon into a versatile technological platform.

Mathematical Models

Electroporation-based technologies constitute a particularly interesting research area at the intersection of applied mathematics and bioelectrical engineering, with important applications in drug and gene delivery, electrochemotherapy,…

Biology

Contribution by Rols & Mir — coming soon

Past, Present & Future

Contribution by Mir — coming soon